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Anavi-Goffer S, BaillieG, Irving AJ, Gertsch J, Greig IR, Pertwee RG, Ross RA. Modulation of L-α-lysophosphatidylinositol /GPR55 MAP kinase signalling by cannabinoids. J. Biol. Chem. 2012; 287, 91-104. Link to article.

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Davey AE, Leach K, Valant C, Conigrave AD, Sexton PM, Christopoulos A. Positive and Negative Allosteric Modulators Promote Biased Signaling at the Calcium-Sensing Receptor. Endocrinol. 2012,153(3):1232-41. Link to article.

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Halai R, Croker DE, Suen JY, Fairlie DP, Cooper MA. A Comparative Study of Impedance versus Optical Label-Free Systems Relative to Labelled Assays in a Predominantly Gi Coupled GPCR (C5aR) Signalling. Biosensors. 2012, 2(3), 273-290. Link to article.

Harikumar KG, Wootten D, Pinon DI, Koole C, Ball AM, Furness SGB, Graham B, Dong M, Christopoulos A, Miller LJ, Sexton PM. Glucagon-like peptide-1 receptor dimerization differentially regulates agonist signaling but does not affect small molecule allostery.
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Koole C, Wootten D, Simms J, Miller LJ, Christopoulos A, Sexton PM. The second extracellular loop of the human glucagon-like peptide-1 receptor (GLP-1R) has a critical role in GLP-1 peptide binding and receptor activation. J. Biol. Chem (2012), 287(6):3642-58. Link to article.

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Leach K, Wen A, Davey AE, Sexton PM, Conigrave AD, Christopoulos A. Identification of Molecular Phenotypes and Biased Signaling Induced by Naturally Occurring Mutations of the Human Calcium-Sensing Receptor. Endocrinology, 2012; 153(9), 4304-4316. Link to article.

Li Z, Blad CC, van der Sluis RJ, de Vries H, Van Berkel TJC, IJzerman AP, Hoekstra M. Effects of pyrazole partial agonists on HCA2-mediated flushing and VLDL-triglyceride levels in mice. Br. J. Pharmacol. 2012; 167(4), 818-825. Link to article.

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Luedtke RR, Mishra Y, Wang O, Griffin SA, Bell-Horner C, Taylor M, Vangveravong S, Dillon GH, Huang R-O, Reichert DE, Mach RH. Comparison of the binding and functional properties of two structurally different D2 dopamine receptor subtype selective compounds. ACS Chem. Neurosci. 2012, In Press. Link to article.

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Sharir H, Console-Bram L, Mundy C, Popoff SN, Kapur A, Abood ME. The Endocannabinoids Anandamide and Virodhamine Modulate the Activity of the Candidate Cannabinoid Receptor GPR55. J Neuroimmune Pharmacol. 2012. Link to article.

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Tulio, AZ, Chang C, Edirisinghe I, White KD, Jablonski JE, Banaszewski K, Kangath A, Tadapaneni RK, Burton-Freeman B, Jackson LS. Berry Fruits Modulated Endothelial Cell Migration and Angiogenesis via Phosphoinositide-3 Kinase/Protein Kinase B Pathway in Vitro in Endothelial Cells. J. Ag. Food. Chem. 60(23), 5803–5812. Link to article.

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Zhan YZ, Zhang YM, Liu CC, Zhang J, Smith WW, Wang N, Chen YN, Zheng L, He LC. A novel taspine derivative, HMQ1611 inhibits breast cancer cell growth via estrogen receptor α and epidermal growth factor receptor signaling pathways. Cancer Prev. Res. 2012, 5(6); 864–873.Link to article.

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Last updated: Nov 2012