TGR BIOSCIENCES ANNOUNCES LICENSE AGREEMENT WITH PRIME DIAGNOSTICS

Adelaide-based biotechnology company, TGR BioSciences, has today announced its second European license agreement since being granted a US Patent for its innovative CaptSure™ technology immunoassay earlier this year.

The license agreement with Prime Diagnostics, a developer of high-quality diagnostics, technologies and services for the agricultural sector, part of Wageningen UR in the Netherlands, will provide Prime Diagnostics with non-exclusive access to TGR’s CaptSure™ technology for use in its immunoassay products for the agricultural sector.

Under the agreement, TGR will also provide antibody conjugation services, which will allow Prime Diagnostics to access TGR’s proprietary antibody tagging and immobilisation technology.

Anne Hinton, CEO of TGR BioSciences, said that the license agreement would bring the two companies closer together and enable further collaboration.

“The association of TGR with Prime Diagnostics brings together two companies with complementary expertise,” she said.

“We look forward to expanding our relationship with Prime Diagnostics further, through the combination of our resources.”

In comparison to conventional assays, which usually involve three separate incubations over 2-3 days or more, CaptSure™ technology only requires a single incubation period and can be performed within an hour, without compromising sensitivity or quality. The simple and robust format of CaptSure™ greatly reduces the costs of labour in medium- and high-throughput screening laboratories and delivers more flexibility for planning of QA/QC operations to the industry. Therefore CaptSure™ technology is the new gold standard for high-throughput immunoassay technology development around the world.

Mrs. Jose van Beckhoven, Product Manager, Prime Diagnostics said that CaptSure™ technology is a welcome addition to their product line, primarily due to its speed and accuracy.

“Our tests, using CaptSure™ immunoassays to find key plant virus targets, have shown the TGR system to be sensitive and fast.”

“Prime Diagnostics is very pleased to be an early adopter of this technology to bring next-generation products to the potato, horticultural and ornamental industry for virus and bacteria detection.”

Established in 2001, TGR BioSciences Pty Ltd (TGR) is a private company located in Adelaide, Australia. TGR provides innovative solutions for biological research applications, with expertise in cell biology, biochemistry and immunoassay design. TGRs high quality products have been used successfully in drug discovery programs around the world.

TGR BIOSCIENCES ANNOUNCES US PATENT GRANTED FOR ‘GOLD STANDARD’ IMMUNOASSAY TECHNOLOGY

TGR BioSciences Pty Ltd (TGR) is pleased to announce the award of patent protection for a faster and more sensitive immunoassay. The assay has a wide range of potential applications, from clinical diagnostics to the detection of plant diseases.

TGR’s CaptSure™ technology was granted a US Patent (9,086,407) on 21 July 2015, giving TGR exclusive rights to licence the technology to researchers and manufacturers around the world.

Director of TGR, Dr Michael Crouch, said that CaptSure™ technology improves the performance of standard immunoassays by providing a shorter incubation period without compromising sensitivity or quality.

“CaptSure™ improves both the speed and accuracy of these immunoassays by reducing the number of steps required to carry out a test — this results in less interference when measuring complex samples,” he said.

As opposed to conventional multi-incubation and multi-wash immunoassays, TGR’s CaptSure™ technology format requires only a single incubation and wash step — made possible by incubating the sample with both ‘capture’ and ‘detector’ antibodies at the same time. This reduces the overall assay time significantly compared to conventional assays.

In addition, the CaptSure™ technology also greatly reduces the costs of manufacturing these tests, by simplifying test development as well as reducing the amount of core reagents required.

The award of this new patent means TGR can now broaden its partnerships with other bio-manufacturing companies and laboratories to expand the use of CaptSure™ technology.

TGR BIOSCIENCES ANNOUNCES LICENSE AGREEMENT WITH DSMZ FOR PLANT VIRUS DETECTION TECHNOLOGY

TGR BioSciences Pty Ltd (TGR) is pleased to announce a license agreement with one of the largest biological resource centers in the world, the Leibniz Institute DSMZ.

With a major focus on plant virus resistance and diagnostics, particularly in an agricultural setting, its license with TGR BioSciences will provide DSMZ with non-exclusive access to TGR’s CaptSure™ technology for use in plant virus immunoassays.

Based in Braunschweig, Germany, DSMZ is not only Europe’s most comprehensive bio-resource center, with a collection of almost 40,000 items from human and animal cell lines to plant cell lines and viruses, it is also a state-of-the-art research institute.

Under the agreement, TGR will also provide antibody conjugation services, allowing DSMZ to access TGR’s proprietary antibody tagging and immobilisation technology.

Anne Hinton, CEO of TGR BioSciences, said that the license agreement shows the breadth of interest in TGR’s CaptSure™ technology, due to its broad application across a number of research fields.

“The use of CaptSure™ technology for virus detection in the agricultural sector provides unequivocal evidence of the broad utility of this immunoassay,” Ms Hinton said. “We are very pleased to be working with DSMZ in this important application.”

In comparison to conventional assays, which usually involve three separate incubations over 4-6 hours, CaptSure™ assays require only a single incubation period and can be performed within an hour, without compromising sensitivity or quality.

CaptSure™ technology also greatly reduces the costs of manufacturing these tests, by simplifying development and the amount of core ingredients required — making it the new gold standard for immunoassay technology development around the world.

Dr Wulf Menzel, Group Leader, Plant Virus Department at DSMZ said that after extensive testing, CaptSure™ technology was by far the most efficient immunoassay for their applications.

“We have extensively tested TGR’s CaptSure™ technology for our application in detecting several plant viruses,” Dr Menzel said.

“It has allowed us to produce assays with significant acceleration in speed, enabling efficient manufacturing for the development of kits for our large client base.

“We look forward to working closely with TGR in the future as we expand our assay base with CaptSure™ technology – we are planning to offer this new technology soon to the plant virus diagnostics sector under the name B-Fast ELISA”.

CONTACT:

TGR BioSciences
General Enquiries
Thebarton, SA, Australia
E. info@tgrbio.com

Leibniz Institute DSMZ
Plant Virus Department
Braunschweig, Germany
E. plantvirus@dsmz.de

TGR BioSciences Collaborates with PerkinElmer in Launch of New AlphaLISA® SureFire® Ultra Assays

PerkinElmer’s Advanced Offering Reduces Assay Time By Up to 50 Percent and Enhances Detection Process for Life Science Researchers

WHAT:

TGR BioSciences, a leading innovator of immunoassay technologies and products, today announced a collaboration with PerkinElmer, Inc. in PerkinElmer’s launch of its AlphaLISA® SureFire® Ultra™ assays. These solutions are designed to reduce assay time by up to 50 percent and to improve the protein phosphorylation detection process. This is a critical process for helping life science professionals obtain more accurate results in biotherapeutic drug discovery research.

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Innova Biosciences and TGR BioSciences Announce Co-Marketing Agreement for Core Technologies

Combining Innova’s Lightning-Link® conjugation kits with TGR’s CaptSure™ ELISA technology simplifies ELISA development and improves sensitivity.

Cambridge, UK and Adelaide, Australia, 16 January 2014: TGR BioSciences Pty Ltd (TGR), a life sciences company focused on the development of rapid, high sensitivity ELISA systems using their CaptSure technology, and Innova Biosciences (Innova), a specialist provider of bioconjugation systems, announced that they have entered into an agreement to promote and co-market each other’s highly complementary technologies, providing customers with a major step forward in simplifying the ELISA development process, while improving sensitivity and reducing costs.

TGR has determined that combining Innova’s Lightning-Link conjugation kits for the horseradish peroxidase (HRP) labelling of antibodies with its CaptSure technology in the development of ELISA systems maximises assay sensitivity, whilst enabling the development of a wide range of ELISA assays rapidly and cost effectively. As part of the agreement Innova customers will be introduced to the CaptSure technology, with the assurance that it will work alongside the Lightning-Link reagents. Similarly, TGR customers will receive a recommendation for Lightning-Link, with the knowledge that it will be available for licensing to them, should they choose to use it alongside CaptSure products.

TGR’s CaptSure technology simplifies ELISA assays to one-step procedures, making them much faster and easier to carry out. Both assay antibodies are added to analyte at once, and after a single wash step the HRP substrate is added to develop the signal. Importantly, costs of manufacture are greatly reduced, since only a single assay plate is required (coated with CaptSure reagent) rather than a different plate for each target, and the system also requires much less assay antibodies.

Innova’s Lightning-Link conjugation system provides the ability to label antibodies with only 30 seconds hands-on time, whilst offering 100% yields and enhanced sensitivity over traditional labelling techniques and over other conjugation systems on the market.

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TGR BioSciences Announces License Agreement with Abcam

TGR BioSciences Pty Ltd (TGR), a leading developer of advanced cell based assay technologies, is pleased to announce a license agreement with Abcam plc, of Cambridge, UK, a producer and distributor of high quality protein research tools. Under the agreement Abcam will develop and manufacture immunoassay products that incorporate TGR’s proprietary CaptSure™ assay technology. Immunoassays incorporating CaptSure are highly sensitive, offer considerable time savings, and are easy to perform when compared with conventional sandwich immunoassays.

James Murray, General Manager of Abcam Eugene commented: “We are pleased to have signed the license agreement with TGR. This innovative technology will enable Abcam to continue to develop its high quality immunoassay range by providing even greater choice to customers.”

“We’re extremely pleased that Abcam, a company at the forefront of product supply and support, has recognised the significant advantages afforded by our CaptSure immunoassay technology,” says Anne Hinton, CEO at TGR BioSciences. “Abcam is recognized around the world for providing the highest quality products and services to the Life Science community, and we are very excited to see Abcam incorporating our technology in their immunoassay products.”